James Van Brocklyn: search on Z-Library

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1

Sphingosine-1-Phosphate Activates Phospholipase D in Human Airway Epithelial Cells via a G Protein-Coupled Receptor

Silvia Orlati, Anna M. Porcelli, Silvana Hrelia, James R. Van Brocklyn, Sarah Spiegel, Michela Rugolo

Journal:

Archives of Biochemistry and Biophysics

Year:

2000

Language:

english

File:

PDF, 142 KB

english, 2000

2

Subtype-specific Residues Involved in Ligand Activation of the Endothelial Differentiation Gene Family Lysophosphatidic Acid Receptors

Valentine, William J., Fells, James I., Perygin, Donna H., Mujahid, Sana, Yokoyama, Kazuaki, Fujiwara, Yuko, Tsukahara, Ryoko, Van Brocklyn, James R., Parrill, Abby L., Tigyi, Gabor

Journal:

Journal of Biological Chemistry

Year:

2008

Language:

english

File:

PDF, 1.10 MB

english, 2008

3

Gangliosides inhibit platelet-derived growth-factor-stimulated increases in intracellular calcium in Swiss 3T3 cells

Zhen Guan, Bradford T. Stokes, James Van Brocklyn, Allan J. Yates

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

1992

Language:

english

File:

PDF, 370 KB

english, 1992

4

Gangliosides Inhibit Platelet-Derived Growth Factor-Stimulated Growth, Receptor Phosphorylation, and Dimerization in Neuroblastoma SH-SY5Y Cells

DiAnna L. Hynds, Monica Summers, James Van Brocklyn, M. Sue O'Dorisio, Allan J. Yates

Journal:

Journal of Neurochemistry

Year:

1995

Language:

english

File:

PDF, 847 KB

english, 1995

5

Ganglioside modulation of the PDGF receptor

Allan J. Yates, Hany E. Saqr, James Van Brocklyn

Journal:

Journal of Neuro-Oncology

Year:

1995

Language:

english

File:

PDF, 983 KB

english, 1995

6

An IgM-kappa rat monoclonal antibody specific for the type 1 sphingosine 1-phosphate G protein-coupled receptor with antagonist and agonist activities

Edward J Goetzl, Dale Dembrow, James R Van Brocklyn, Markus Gráler, Mei-Chuan Huang

Journal:

Immunology Letters

Year:

2004

Language:

english

File:

PDF, 354 KB

english, 2004

7

Corrigendum to “Sphingosine 1-phosphate pKa and binding constants: Intramolecular and intermolecular influences” [J. Mol. Graph. Model. 26 (2009) 519–528]

Mor M. Naor, Michelle D. Walker, James R. Van Brocklyn, Gabor Tigyi, Abby L. Parrill

Journal:

Journal of Molecular Graphics and Modelling

Year:

2009

Language:

english

File:

PDF, 51 KB

english, 2009

8

The selective Aurora-A kinase inhibitor MLN8237 (alisertib) potently inhibits proliferation of glioblastoma neurosphere tumor stem-like cells and potentiates the effects of temozolomide and ionizing radiation

Hong, Xin, O’Donnell, James P., Salazar, Clarence R., Van Brocklyn, James R., Barnett, Kahlil D., Pearl, Dennis K., deCarvalho, Ana C., Ecsedy, Jeffrey A., Brown, Stephen L., Mikkelsen, Tom, Lehman, N

Journal:

Cancer Chemotherapy and Pharmacology

Year:

2014

Language:

english

File:

PDF, 1.04 MB

english, 2014

9

Text mining of full-text journal articles combined with gene expression analysis reveals a relationship between sphingosine-1-phosphate and invasiveness of a glioblastoma cell line

Jeyakumar Natarajan, Daniel Berrar, Werner Dubitzky, Catherine Hack, Yonghong Zhang, Catherine DeSesa, James R Van Brocklyn, Eric G Bremer

Journal:

BMC Bioinformatics

Year:

2006

Language:

english

File:

PDF, 582 KB

english, 2006

10

The role of sphingosine kinase-1 in EGFRvIII-regulated growth and survival of glioblastoma cells

Adriana Estrada-Bernal, Sean E. Lawler, Michal O. Nowicki, Abhik Ray Chaudhury, James R. Van Brocklyn

Journal:

Journal of Neuro-Oncology

Year:

2011

Language:

english

File:

PDF, 659 KB

english, 2011

11

Sphingosine-1-Phosphate in Cell Growth and Cell Death

SARAH SPIEGEL, OLIVIER CUVILLIER, LISA C. EDSALL, TAKAFUMI KOHAMA, RAMIL MENZELEEV, ZOLTAN OLAH, ANA OLIVERA, GRISHA PIRIANOV, DIANNE M. THOMAS, ZHENXING TU, JAMES R. VAN BROCKLYN, FANG WANG

Journal:

Annals of the New York Academy of Sciences

Year:

1998

File:

PDF, 792 KB

1998

12

Sphingosine-1-phosphate stimulates human glioma cell proliferation through Gi-coupled receptors: role of ERK MAP kinase and phosphatidylinositol 3-kinase β

James R Van Brocklyn, Catherine A Letterle, Pamela J Snyder, Thomas W Prior

Journal:

Year:

2002

Language:

english

File:

PDF, 274 KB

english, 2002

13

Homodimerization and heterodimerization of S1P/EDG sphingosine-1-phosphate receptors

James R Van Brocklyn, Babak Behbahani, Norman H Lee

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2002

Language:

english

File:

PDF, 205 KB

english, 2002

14

Sphingolipid Signaling Pathways as Potential Therapeutic Targets in Gliomas

Van Brocklyn, James

Journal:

Mini Reviews in Medicinal Chemistry

Year:

2007

Language:

english

File:

PDF, 243 KB

english, 2007

15

Sphingosine Kinase-1 Expression Correlates With Poor Survival of Patients With Glioblastoma Multiforme: Roles of Sphingosine Kinase Isoforms in Growth of Glioblastoma Cell Lines

Van Brocklyn, James R, Jackson, Catherine A, Pearl, Dennis K, Kotur, Mark S, Snyder, Pamela J, Prior, Thomas W

Journal:

Journal of Neuropathology and Experimental Neurology

Year:

2005

Language:

english

File:

PDF, 452 KB

english, 2005

16

Sphingosine-1-phosphate is a ligand for the G protein-coupled receptor EDG-6

Van Brocklyn, James R., GraÌler, Markus H., Bernhardt, GuÌnter, Hobson, John P., Lipp, Martin, Spiegel, Sarah

Journal:

Year:

2000

File:

PDF, 159 KB

2000

17

N , N -Dimethylsphingosine Is a Potent Competitive Inhibitor of Sphingosine Kinase but Not of Protein Kinase C: Modulation of Cellular Levels of Sphingosine 1-Phosphate and Ceramide †

Edsall, Lisa C., Van Brocklyn, James R., Cuvillier, Olivier, Kleuser, Burkhard, Spiegel, Sarah

Journal:

Year:

1998

Language:

english

File:

PDF, 261 KB

english, 1998

18

The control of the balance between ceramide and sphingosine-1-phosphate by sphingosine kinase: Oxidative stress and the seesaw of cell survival and death

James R. Van Brocklyn, Joseph B. Williams

Journal:

Comparative Biochemistry and Physiology Part B: Biochemistry and Molecular Biology

Year:

2012

Language:

english

File:

PDF, 697 KB

english, 2012

19

Structural Features of EDG1 Receptor-Ligand Complexes Revealed by Computational Modeling and Mutagenesis

ABBY L. PARRILL, DANIEL L. BAKER, DE-AN WANG, DAVID J. FISCHER, DEBRA L. BAUTISTA, JAMES VAN BROCKLYN, SARAH SPIEGEL, GABOR TIGYI

Journal:

Annals of the New York Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 4.33 MB

english, 2000

20

Roles of sphingosine-1-phosphate (S1P) receptors in malignant behavior of glioma cells. Differential effects of S1P2 on cell migration and invasiveness

Nicholas Young, James R. Van Brocklyn

Journal:

Experimental Cell Research

Year:

2007

Language:

english

File:

PDF, 925 KB

english, 2007

21

Dual Actions of Sphingosine-1-Phosphate: Extracellular through the Gi-Coupled Receptor Edg-1 and Intracellular to Regulate Proliferation and Survival

James R. Van Brocklyn, Menq-Jer Lee, Ramil Menzeleev, Ana Olivera, Lisa Edsall, Olivier Cuvillier, Dianne M. Thomas, Peter J. P. Coopman, Shobha Thangada, Catherine H. Liu, Timothy Hla and Sarah Spieg

Journal:

The Journal of Cell Biology

Year:

1998

Language:

english

File:

PDF, 1.08 MB

english, 1998

22

Cellular Metabolic Rate Is Influenced by Life-History Traits in Tropical and Temperate Birds

Jimenez, Ana Gabriela, Van Brocklyn, James, Wortman, Matthew, Williams, Joseph B., Sears, Michael

Journal:

Year:

2014

Language:

english

File:

PDF, 523 KB

english, 2014

23

Sphingosine 1-phosphate pKa and binding constants: Intramolecular and intermolecular influences

Mor M. Naor, Michelle D. Walker, James R. Van Brocklyn, Gabor Tigyi, Abby L. Parrill

Journal:

Journal of Molecular Graphics and Modelling

Year:

2007

Language:

english

File:

PDF, 502 KB

english, 2007

24

MicroRNA-451 Regulates LKB1/AMPK Signaling and Allows Adaptation to Metabolic Stress in Glioma Cells

Jakub Godlewski, Michal O. Nowicki, Agnieszka Bronisz, Gerard Nuovo, Jeff Palatini, Michael De Lay, James Van Brocklyn, Michael C. Ostrowski, E. Antonio Chiocca, Sean E. Lawler

Journal:

Year:

2010

Language:

english

File:

PDF, 1.80 MB

english, 2010

25

Sphingosine-1-phosphate stimulates motility and invasiveness of human glioblastoma multiforme cells

James R. Van Brocklyn, Nicholas Young, Rosemary Roof

Journal:

Year:

2003

Language:

english

File:

PDF, 252 KB

english, 2003

26

Signal Transduction of Sphingosine-1-Phosphate G Protein—Coupled Receptors

Young, Nicholas, Van Brocklyn, James R.

Journal:

The Scientific World JOURNAL

Year:

2006

Language:

english

File:

PDF, 1.13 MB

english, 2006

27

Ganglioside GM1 Activates the Mitogen-Activated Protein Kinase Erk2 and p70 S6 Kinase in U-1242 MG Human Glioma Cells

James R. Van Brocklyn, J. R. Vandenheede, Richard Fertel, Allan J. Yates, Arfaan A. Rampersaud

Journal:

Journal of Neurochemistry

Year:

1997

Language:

english

File:

PDF, 1.26 MB

english, 1997

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